Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.3351 | 0.1454 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.6713 | 0.3472 | 0.5 |
Echinococcus multilocularis | Blood coagulation inhibitor, Disintegrin | 0.1693 | 0.0459 | 0.2017 |
Brugia malayi | Hemopexin family protein | 0.1294 | 0.022 | 0.2836 |
Echinococcus multilocularis | adam 17 protease | 0.2698 | 0.1063 | 0.6856 |
Mycobacterium tuberculosis | Possible exported protein | 0.1256 | 0.0197 | 0.0077 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.6713 | 0.3472 | 0.5 |
Brugia malayi | metalloprotease disintegrin 16 with thrombospondin type I motif | 0.1274 | 0.0208 | 0.268 |
Trypanosoma brucei | Peptide deformylase 2 | 0.6713 | 0.3472 | 0.5 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.2057 | 0.0678 | 1 |
Loa Loa (eye worm) | matrixin family protein | 0.2057 | 0.0678 | 0.2382 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 1.7591 | 1 | 0.5 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.3351 | 0.1454 | 1 |
Schistosoma mansoni | ADAMTS5 peptidase (M12 family) | 0.1274 | 0.0208 | 0.1958 |
Schistosoma mansoni | hypothetical protein | 0.1294 | 0.022 | 0.2073 |
Loa Loa (eye worm) | hypothetical protein | 0.5669 | 0.2846 | 1 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.6713 | 0.3472 | 0.5 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.6713 | 0.3472 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.6713 | 0.3472 | 0.5 |
Toxoplasma gondii | hypothetical protein | 1.7591 | 1 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 1.7591 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 1.7591 | 1 | 1 |
Mycobacterium ulcerans | peptide deformylase | 1.7591 | 1 | 1 |
Echinococcus granulosus | Blood coagulation inhibitor Disintegrin | 0.1693 | 0.0459 | 0.2017 |
Schistosoma mansoni | ADAM17 peptidase (M12 family) | 0.2698 | 0.1063 | 1 |
Loa Loa (eye worm) | matrixin family protein | 0.2222 | 0.0777 | 0.2729 |
Plasmodium vivax | peptide deformylase, putative | 1.7591 | 1 | 0.5 |
Onchocerca volvulus | Matrilysin homolog | 0.2057 | 0.0678 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1129 | 0.0121 | 0.0426 |
Onchocerca volvulus | 0.1294 | 0.022 | 0.325 | |
Plasmodium falciparum | peptide deformylase | 1.7591 | 1 | 0.5 |
Echinococcus granulosus | adam 17 protease | 0.2967 | 0.1224 | 0.8151 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.6713 | 0.3472 | 0.5 |
Brugia malayi | Matrixin family protein | 0.2222 | 0.0777 | 1 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.1129 | 0.0121 | 0.1561 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 1.7591 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.