Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | phosphofructokinase | 0.0118 | 0.1514 | 1 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0032 | 0 | 0.5 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0118 | 0.1514 | 0.5 |
Echinococcus granulosus | geminin | 0.0172 | 0.2477 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0118 | 0.1514 | 1 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0118 | 0.1514 | 0.5 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0032 | 0 | 0.5 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0118 | 0.1514 | 1 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0 | 0.5 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0118 | 0.1514 | 1 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0118 | 0.1514 | 0.5643 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0118 | 0.1514 | 0.5 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0118 | 0.1514 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0118 | 0.1514 | 1 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0032 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic | 0.06 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0118 | 0.1514 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0118 | 0.1514 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0118 | 0.1514 | 0.5643 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0032 | 0 | 0.5 |
Plasmodium falciparum | nicotinamide/nicotinic acid mononucleotide adenylyltransferase | 0.06 | 1 | 1 |
Treponema pallidum | hypothetical protein | 0.06 | 1 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0118 | 0.1514 | 1 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0032 | 0 | 0.5 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0118 | 0.1514 | 0.1514 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0118 | 0.1514 | 0.5643 |
Brugia malayi | phosphofructokinase | 0.0118 | 0.1514 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.2477 | 1 |
Mycobacterium ulcerans | bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein | 0.06 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0172 | 0.2477 | 1 |
Plasmodium vivax | nicotinate-nucleotide adenylyltransferase, putative | 0.06 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0118 | 0.1514 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.2477 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0118 | 0.1514 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0118 | 0.1514 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0118 | 0.1514 | 0.5643 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.