Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | TNFR CD27 30 40 95 cysteine rich region | 0.0044 | 0.3527 | 0.5 |
Echinococcus multilocularis | tumor necrosis factor receptor superfamily | 0.0044 | 0.3527 | 0.5 |
Plasmodium vivax | serine/threonine protein kinase, putative | 0.0072 | 1 | 0.5 |
Trypanosoma cruzi | Eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0072 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0029 | 0 | 0.5 |
Trypanosoma cruzi | Eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0072 | 1 | 1 |
Schistosoma mansoni | tumor necrosis factor receptor related | 0.0044 | 0.3527 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0072 | 1 | 0.5 |
Trypanosoma brucei | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0072 | 1 | 0.5 |
Echinococcus granulosus | tumor necrosis factor receptor superfamily | 0.0044 | 0.3527 | 0.5 |
Echinococcus granulosus | TNFR CD27 30 40 95 cysteine rich region | 0.0044 | 0.3527 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0072 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.