Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0105 | 0.6421 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0683 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0134 | 0.8595 | 0.8595 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0105 | 0.6421 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.6421 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0153 | 1 | 1 |
Giardia lamblia | Kinase, PLK | 0.0105 | 0.6421 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.6421 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0105 | 0.6421 | 0.6421 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0134 | 0.8595 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0153 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0683 | 0.1064 |
Schistosoma mansoni | kinase | 0.0053 | 0.2573 | 0.2573 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.6421 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0683 | 0.5 |
Trypanosoma brucei | polo-like protein kinase | 0.0105 | 0.6421 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0105 | 0.6421 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.6421 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0105 | 0.6421 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0683 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.6421 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0105 | 0.6421 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0105 | 0.6421 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0105 | 0.6421 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0683 | 0.1064 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0105 | 0.6421 | 0.7471 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.6421 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0134 | 0.8595 | 0.8595 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0105 | 0.6421 | 0.6421 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0105 | 0.6421 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0683 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.