Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Melatonin receptor type 1A | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0165 | 0 | 0.5 |
Brugia malayi | Dopamine receptor protein 2 | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | RE15519p | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | Serotonin receptor | 0.0165 | 0 | 0.5 |
Echinococcus multilocularis | kinesin family 1 | 0.0201 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0165 | 0 | 0.5 |
Brugia malayi | larval opioid receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | G-protein coupled receptor | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0165 | 0 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | G-protein coupled receptor | 0.0165 | 0 | 0.5 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | Dopamine receptor protein 1 | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | ORL1-like opioid receptor | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | GnHR receptor homolog | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | follicle stimulating hormone receptor | 0.0165 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.2829 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | sulfakinin receptor protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | G protein-coupled receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | Dopamine receptor | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0165 | 0 | 0.5 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Onchocerca volvulus | 0.0165 | 0 | 0.5 | |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Brugia malayi | AKH receptor | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 79.4328 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.