Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | serine/threonine protein kinase | 0.0191 | 0.2782 | 0.2782 |
Trypanosoma cruzi | cyclin 6, putative | 0.033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Trichomonas vaginalis | cyclins, putative | 0.0226 | 0.4577 | 0.4577 |
Trichomonas vaginalis | cyclins, putative | 0.033 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | animal heme peroxidase | 0.027 | 0.6844 | 0.6844 |
Brugia malayi | Protein kinase domain containing protein | 0.0191 | 0.2782 | 0.2782 |
Brugia malayi | cell division control protein 2 homolog | 0.0191 | 0.2782 | 0.2782 |
Echinococcus granulosus | cyclin dependent kinase | 0.0191 | 0.2782 | 0.2782 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Entamoeba histolytica | cyclin, putative | 0.033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Brugia malayi | Animal haem peroxidase family protein | 0.027 | 0.6844 | 0.6844 |
Echinococcus multilocularis | peroxidasin | 0.027 | 0.6844 | 0.6844 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0191 | 0.2782 | 0.2782 |
Trichomonas vaginalis | cyclin B, putative | 0.033 | 1 | 1 |
Schistosoma mansoni | cyclin B | 0.033 | 1 | 1 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Echinococcus granulosus | cyclin B | 0.033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.027 | 0.6844 | 0.6844 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 1 | 1 |
Brugia malayi | Cyclin, N-terminal domain containing protein | 0.033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Brugia malayi | Animal haem peroxidase family protein | 0.027 | 0.6844 | 0.6844 |
Brugia malayi | Animal haem peroxidase family protein | 0.027 | 0.6844 | 0.6844 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0191 | 0.2782 | 0.2782 |
Brugia malayi | Blistered cuticle protein 3 | 0.027 | 0.6844 | 0.6844 |
Trichomonas vaginalis | cyclin B, putative | 0.033 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0191 | 0.2782 | 0.2782 |
Plasmodium vivax | protein kinase Crk2 | 0.0191 | 0.2782 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Trichomonas vaginalis | cyclins, putative | 0.033 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.033 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.027 | 0.6844 | 0.6844 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0191 | 0.2782 | 0.2782 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0191 | 0.2782 | 0.2782 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0191 | 0.2782 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Brugia malayi | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Leishmania major | cyclin | 0.033 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0191 | 0.2782 | 0.2782 |
Schistosoma mansoni | peroxidasin | 0.027 | 0.6844 | 0.6844 |
Loa Loa (eye worm) | animal heme peroxidase | 0.027 | 0.6844 | 0.6844 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Trichomonas vaginalis | cyclins, putative | 0.033 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.027 | 0.6844 | 0.6844 |
Giardia lamblia | Kinase, CMGC CDK | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Echinococcus multilocularis | cyclin B | 0.033 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.027 | 0.6844 | 0.6844 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Trichomonas vaginalis | cyclin B, putative | 0.033 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.027 | 0.6844 | 0.6844 |
Brugia malayi | Peroxidasin | 0.027 | 0.6844 | 0.6844 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0191 | 0.2782 | 0.2782 |
Trichomonas vaginalis | cyclin A, putative | 0.033 | 1 | 1 |
Leishmania major | CYC2-like cyclin, putative,cyclin 6, putative | 0.033 | 1 | 1 |
Trichomonas vaginalis | cyclins, putative | 0.033 | 1 | 1 |
Trichomonas vaginalis | cyclin B, putative | 0.033 | 1 | 1 |
Trypanosoma cruzi | CYC2-like cyclin, putative | 0.033 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0191 | 0.2782 | 0.2782 |
Echinococcus granulosus | peroxidasin | 0.027 | 0.6844 | 0.6844 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.6844 | 0.6844 |
Giardia lamblia | G2/mitotic-specific cyclin B | 0.033 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0191 | 0.2782 | 0.2782 |
Onchocerca volvulus | 0.033 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.2852 | 0.2852 |
Plasmodium falciparum | protein kinase 5 | 0.0191 | 0.2782 | 1 |
Trypanosoma brucei | mitotic cyclin 6 | 0.033 | 1 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.033 | 1 | 1 |
Trypanosoma cruzi | cyclin, putative | 0.033 | 1 | 1 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0191 | 0.2782 | 0.2782 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.2676 | 0.2676 |
Loa Loa (eye worm) | animal heme peroxidase | 0.027 | 0.6844 | 0.6844 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.