Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Conserved protein | 0.0224 | 0.3228 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Echinococcus granulosus | Transglutaminase | 0.0224 | 0.3228 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Mycobacterium tuberculosis | Long conserved protein | 0.0224 | 0.3228 | 0.5 |
Trichomonas vaginalis | peptide N-glycanase, putative | 0.0224 | 0.3228 | 0.5 |
Echinococcus granulosus | adam 17 protease | 0.0223 | 0.3204 | 0.9926 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0224 | 0.3228 | 0.5 |
Echinococcus multilocularis | adam 17 protease | 0.0203 | 0.2528 | 0.7831 |
Mycobacterium ulcerans | transglutaminase family protein | 0.0224 | 0.3228 | 0.5 |
Echinococcus multilocularis | Transglutaminase | 0.0224 | 0.3228 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0224 | 0.3228 | 1 |
Mycobacterium ulcerans | putative transglutaminase-like protein | 0.0224 | 0.3228 | 0.5 |
Onchocerca volvulus | 0.0224 | 0.3228 | 0.5 | |
Giardia lamblia | Transglutaminase/protease, putative | 0.0224 | 0.3228 | 0.5 |
Brugia malayi | Thioredoxin family protein | 0.0224 | 0.3228 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.