Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.046 | 0.6224 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.046 | 0.6224 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.046 | 0.6224 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.046 | 0.6224 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.046 | 0.6224 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.046 | 0.6224 | 0.5 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.046 | 0.6224 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.046 | 0.6224 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.046 | 0.6224 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.046 | 0.6224 | 0.5 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.046 | 0.6224 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.046 | 0.6224 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.046 | 0.6224 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.046 | 0.6224 | 0.5 |
Echinococcus granulosus | Serine:threonine protein kinase PLK4 | 0.0362 | 0.444 | 0.7128 |
Trichomonas vaginalis | CAMK family protein kinase | 0.046 | 0.6224 | 1 |
Giardia lamblia | Kinase, PLK | 0.046 | 0.6224 | 0.5 |
Echinococcus multilocularis | Serine:threonine protein kinase PLK4 | 0.0362 | 0.444 | 0.7135 |
Trichomonas vaginalis | CAMK family protein kinase | 0.046 | 0.6224 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.046 | 0.6224 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.