Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.017 | 0.0184 | 0.0184 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0552 | 0.3056 | 0.5 |
Brugia malayi | carbohydrate phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.1473 | 1 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.017 | 0.0184 | 0.0184 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.1473 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0552 | 0.3056 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0552 | 0.3056 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Giardia lamblia | Glycogen phosphorylase | 0.0552 | 0.3056 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.017 | 0.0184 | 0.0184 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.017 | 0.0184 | 0.0184 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0552 | 0.3056 | 0.5 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0238 | 0.0697 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.017 | 0.0184 | 0.0184 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0552 | 0.3056 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.017 | 0.0184 | 0.0184 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.017 | 0.0184 | 0.0184 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0552 | 0.3056 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0238 | 0.0697 | 0.0697 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0552 | 0.3056 | 0.3056 |
Echinococcus granulosus | glycogen phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.1473 | 1 | 1 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0238 | 0.0697 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0552 | 0.3056 | 0.3056 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.1473 | 1 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0552 | 0.3056 | 0.3056 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.