Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | prolyl oligopeptidase | 0.2878 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.2216 | 0.6981 | 0.6262 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.2878 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1107 | 0.1923 | 0.0816 |
Echinococcus granulosus | prolyl endopeptidase | 0.2216 | 0.6981 | 0.6262 |
Loa Loa (eye worm) | hypothetical protein | 0.2216 | 0.6981 | 0.6981 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.2216 | 0.6981 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.2216 | 0.6981 | 0.6262 |
Trypanosoma cruzi | prolyl endopeptidase | 0.2216 | 0.6981 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1107 | 0.1923 | 0.0816 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.1794 | 0.5057 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.2216 | 0.6981 | 0.6262 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.2878 | 1 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1107 | 0.1923 | 0.0816 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1107 | 0.1923 | 0.0816 |
Trypanosoma brucei | prolyl endopeptidase | 0.2216 | 0.6981 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.2216 | 0.6981 | 1 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.1009 | 0.1474 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.2216 | 0.6981 | 0.6981 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.2878 | 1 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1107 | 0.1923 | 0.0816 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1107 | 0.1923 | 0.1923 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.1009 | 0.1474 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.2878 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.