Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.2848 | 0.6954 | 0.6111 |
Toxoplasma gondii | prolyl endopeptidase | 0.2848 | 0.6954 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.1301 | 0.1406 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1514 | 0.2167 | 0.1371 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1514 | 0.2167 | 0.1371 |
Trypanosoma cruzi | prolyl endopeptidase | 0.2848 | 0.6954 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.2848 | 0.6954 | 0.6111 |
Echinococcus granulosus | prolyl endopeptidase | 0.2848 | 0.6954 | 0.6111 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.3697 | 1 | 1 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.1301 | 0.1406 | 0.5 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.3697 | 1 | 1 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.2848 | 0.6954 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.2848 | 0.6954 | 0.6954 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.3697 | 1 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.3697 | 1 | 1 |
Trypanosoma brucei | prolyl endopeptidase | 0.2848 | 0.6954 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1514 | 0.2167 | 0.1371 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1514 | 0.2167 | 0.2167 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1514 | 0.2167 | 0.1371 |
Loa Loa (eye worm) | hypothetical protein | 0.2848 | 0.6954 | 0.6954 |
Echinococcus multilocularis | prolyl endopeptidase | 0.2848 | 0.6954 | 0.6111 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.2298 | 0.4982 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1514 | 0.2167 | 0.1371 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.3697 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.