Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.1506 | 0.126 | 0.5 |
Toxoplasma gondii | prolyl endopeptidase | 0.3281 | 0.6579 | 1 |
Trypanosoma brucei | prolyl endopeptidase | 0.3281 | 0.6579 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1784 | 0.2094 | 0.1568 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.4422 | 1 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1784 | 0.2094 | 0.1568 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.3281 | 0.6579 | 0.5673 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.1506 | 0.126 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.4422 | 1 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1784 | 0.2094 | 0.1568 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1784 | 0.2094 | 0.2094 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.4422 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.3281 | 0.6579 | 0.6579 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1784 | 0.2094 | 0.1568 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.4422 | 1 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.3281 | 0.6579 | 0.5673 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.4422 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.3281 | 0.6579 | 0.5673 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.2637 | 0.4649 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1784 | 0.2094 | 0.1568 |
Loa Loa (eye worm) | hypothetical protein | 0.3281 | 0.6579 | 0.6579 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.3281 | 0.6579 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.3281 | 0.6579 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.3281 | 0.6579 | 0.5673 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.