Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.3525 | 0.4193 | 0.4193 |
Loa Loa (eye worm) | hypothetical protein | 0.4423 | 0.6088 | 0.6088 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.4423 | 0.6088 | 0.5108 |
Trypanosoma brucei | prolyl endopeptidase | 0.4423 | 0.6088 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.2487 | 0.2002 | 0.1861 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.2045 | 0.1069 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.6277 | 1 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.4423 | 0.6088 | 0.5108 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.6277 | 1 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.4423 | 0.6088 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.4423 | 0.6088 | 0.5108 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.6277 | 1 | 1 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.2045 | 0.1069 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.6277 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.2487 | 0.2002 | 0.1861 |
Echinococcus granulosus | prolyl endopeptidase | 0.4423 | 0.6088 | 0.5108 |
Leishmania major | C-8 sterol isomerase-like protein | 0.3525 | 0.4193 | 0.6225 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.3525 | 0.4193 | 0.6225 |
Brugia malayi | prolyl oligopeptidase family protein | 0.4423 | 0.6088 | 0.6088 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.6277 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.2487 | 0.2002 | 0.2002 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.3534 | 0.4212 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.2487 | 0.2002 | 0.1861 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.3525 | 0.4193 | 0.6225 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.2487 | 0.2002 | 0.1861 |
Loa Loa (eye worm) | hypothetical protein | 0.3525 | 0.4193 | 0.4193 |
Loa Loa (eye worm) | hypothetical protein | 0.1802 | 0.0556 | 0.0556 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.4423 | 0.6088 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.2487 | 0.2002 | 0.1861 |
Toxoplasma gondii | prolyl endopeptidase | 0.4423 | 0.6088 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.