Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.025 | 0.2188 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0324 | 0.3888 | 0.287 |
Trypanosoma brucei | prolyl endopeptidase | 0.0324 | 0.3888 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0324 | 0.3888 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0217 | 0.1428 | 0.3673 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0217 | 0.1428 | 0.3673 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0217 | 0.1428 | 0.3673 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0588 | 1 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0324 | 0.3888 | 0.287 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0588 | 1 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.0324 | 0.3888 | 0.287 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0588 | 1 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0324 | 0.3888 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0588 | 1 | 1 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0155 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0155 | 0 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0588 | 1 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0217 | 0.1428 | 0.3673 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0324 | 0.3888 | 0.287 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0324 | 0.3888 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0324 | 0.3888 | 0.287 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0217 | 0.1428 | 0.3673 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.