Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0064 | 0.051 | 0.0784 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0064 | 0.051 | 0.0784 |
Trypanosoma brucei | prolyl endopeptidase | 0.0128 | 0.6507 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0128 | 0.6507 | 1 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0104 | 0.4241 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0128 | 0.6507 | 0.632 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0166 | 1 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.0128 | 0.6507 | 0.632 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0128 | 0.6507 | 0.632 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0064 | 0.051 | 0.0784 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0166 | 1 | 1 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0058 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0058 | 0 | 0.5 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0166 | 1 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0128 | 0.6507 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0166 | 1 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0064 | 0.051 | 0.0784 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0128 | 0.6507 | 0.632 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0128 | 0.6507 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0128 | 0.6507 | 0.632 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0064 | 0.051 | 0.0784 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0166 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.