Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0435 | 1 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.035 | 0.7145 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0345 | 0.7003 | 0.6203 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.035 | 0.7145 | 0.6382 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0435 | 1 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0345 | 0.7003 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0198 | 0.2107 | 0.227 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.035 | 0.7145 | 1 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0135 | 0 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0345 | 0.7003 | 0.9783 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0345 | 0.7003 | 1 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0217 | 0.2734 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0345 | 0.7003 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0345 | 0.7003 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0345 | 0.7003 | 0.6203 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0345 | 0.7003 | 0.6203 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.2107 | 0.227 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.1881 | 0.1924 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.035 | 0.7145 | 0.6382 |
Brugia malayi | prolyl oligopeptidase family protein | 0.035 | 0.7145 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0345 | 0.7003 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.035 | 0.7145 | 0.6382 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.