Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Giardia lamblia | Thymus-specific serine protease precursor | 0.0314 | 0.2015 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.144 | 1 | 1 |
Giardia lamblia | Serine peptidase, putative | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.144 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0314 | 0.2015 | 0.2015 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0314 | 0.2015 | 0.2015 |
Trypanosoma cruzi | putative prolyl carboxypeptidase, putative | 0.0314 | 0.2015 | 0.5 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.144 | 1 | 1 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0314 | 0.2015 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase S28, putative | 0.0314 | 0.2015 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.144 | 1 | 1 |
Echinococcus granulosus | smoothened | 0.0673 | 0.456 | 0.456 |
Schistosoma mansoni | lysosomal Pro-Xaa carboxypeptidase (S28 family) | 0.144 | 1 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.144 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0314 | 0.2015 | 0.2015 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0659 | 0.4461 | 0.4461 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0314 | 0.2015 | 0.5 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0314 | 0.2015 | 0.2015 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0314 | 0.2015 | 0.5 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0314 | 0.2015 | 0.5 |
Echinococcus multilocularis | smoothened | 0.0673 | 0.456 | 0.456 |
Trypanosoma cruzi | serine carboxypeptidase S28, putative | 0.0314 | 0.2015 | 0.5 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0314 | 0.2015 | 0.5 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | lysosomal pro-X carboxypeptidase, putative | 0.0314 | 0.2015 | 0.5 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0314 | 0.2015 | 0.2015 |
Onchocerca volvulus | 0.0314 | 0.2015 | 0.5 | |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0314 | 0.2015 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0314 | 0.2015 | 0.5 |
Toxoplasma gondii | serine carboxypeptidase s28 protein | 0.0314 | 0.2015 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.2015 | 0.2015 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | 0 uM | Inhibition of prolyl 4-hydroxylase; No data | ChEMBL. | 1321909 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.