Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | epidermal growth factor receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.04 | 0.04 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.018 | 0.1285 | 0.1285 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0097 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0377 | 0.3351 | 0.3351 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0797 | 0.7757 | 0.7757 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0411 | 0.0411 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.04 | 0.04 |
Schistosoma mansoni | calcium-activated potassium channel | 0.1011 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.018 | 0.1285 | 0.1285 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.1011 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.3803 | 0.3803 |
Schistosoma mansoni | hypothetical protein | 0.1011 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1011 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0096 | 0.04 | 0.04 |
Echinococcus granulosus | epidermal growth factor receptor | 0.018 | 0.1285 | 0.1285 |
Schistosoma mansoni | tyrosine kinase | 0.0097 | 0.0411 | 0.0411 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0097 | 0.0411 | 0.0411 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0097 | 0.0411 | 0.0411 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.018 | 0.1285 | 0.1285 |
Loa Loa (eye worm) | hypothetical protein | 0.0173 | 0.1212 | 0.1212 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.018 | 0.1285 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.