Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0677 | 0.1583 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0196 | 0.4277 | 1 |
Brugia malayi | hypothetical protein | 0.005 | 0.0677 | 0.1583 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0073 | 0.0688 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0073 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0066 | 0.1061 | 0.1061 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.013 | 0.2633 | 0.2633 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0196 | 0.4277 | 0.4277 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0066 | 0.1061 | 1 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0196 | 0.4277 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0429 | 1 | 1 |
Giardia lamblia | Thymus-specific serine protease precursor | 0.0023 | 0 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0196 | 0.4277 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0066 | 0.1061 | 1 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.0166 | 0.3517 | 0.3517 |
Schistosoma mansoni | alkaline phosphatase | 0.0166 | 0.3517 | 0.3517 |
Echinococcus multilocularis | alkaline phosphatase | 0.0166 | 0.3517 | 0.3517 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0023 | 0 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0196 | 0.4277 | 0.4277 |
Schistosoma mansoni | hypothetical protein | 0.0086 | 0.1554 | 0.1554 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.0166 | 0.3517 | 0.3517 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0 | 0.5 |
Giardia lamblia | Serine peptidase, putative | 0.0023 | 0 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0066 | 0.1061 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0073 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.014 | 0.289 | 0.289 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.0166 | 0.3517 | 0.3517 |
Echinococcus granulosus | alkaline phosphatase | 0.0166 | 0.3517 | 0.3517 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0066 | 0.1061 | 0.2481 |
Schistosoma mansoni | thyroid hormone receptor | 0.014 | 0.289 | 0.289 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0023 | 0 | 0.5 |
Schistosoma mansoni | alkaline phosphatase | 0.0166 | 0.3517 | 0.3517 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.013 | 0.2633 | 0.2633 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | lysosomal pro-X carboxypeptidase, putative | 0.0023 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.2633 | 0.2633 |
Schistosoma mansoni | thyroid hormone receptor | 0.014 | 0.289 | 0.289 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0066 | 0.1061 | 0.1061 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0073 | 0.0688 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Entamoeba histolytica | serine carboxypeptidase (S28) family protein | 0.0023 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0073 | 0.0171 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0073 | 0.0688 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.0429 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0196 | 0.4277 | 0.4277 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0073 | 0.0171 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0 | 0.5 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.0166 | 0.3517 | 0.3517 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0066 | 0.1061 | 0.1061 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.0166 | 0.3517 | 0.3517 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0066 | 0.1061 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0066 | 0.1061 | 1 |
Echinococcus granulosus | intestinal type alkaline phosphatase | 0.0166 | 0.3517 | 0.3517 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0066 | 0.1061 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0023 | 0 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0073 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.