Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | DNA topoisomerase 1 | 0.0226 | 0.3037 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0081 | 0.0762 | 0.251 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0068 | 0.0551 | 0.1816 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.007 | 0.0578 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Plasmodium vivax | topoisomerase I, putative | 0.0226 | 0.3037 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0107 | 0.1169 | 0.1305 | |
Mycobacterium leprae | Probable orotidine 5'-phosphate decarboxylase PyrF (OMP decarboxylase) (OMPDCase) (OMPdecase) | 0.0067 | 0.053 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0068 | 0.0551 | 0.1816 |
Toxoplasma gondii | DNA topoisomerase I, putative | 0.0226 | 0.3037 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | somatostatin receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | DNA topoisomerase I | 0.0226 | 0.3037 | 1 |
Plasmodium falciparum | topoisomerase I | 0.0226 | 0.3037 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | DNA topoisomerase I | 0.0226 | 0.3037 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0068 | 0.0551 | 0.1816 |
Mycobacterium ulcerans | orotidine 5'-phosphate decarboxylase | 0.0067 | 0.053 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | opsin-like receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0074 | 0.0655 | 0.2156 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | g protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Dopamine receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0107 | 0.1169 | 0.1305 | |
Echinococcus granulosus | g protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | amine GPCR | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | larval opioid receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1169 | 0.3848 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | serotonin receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | orotidine 5'-phosphate decarboxylase | 0.0067 | 0.053 | 0.1747 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | DNA topoisomerase 1 | 0.0226 | 0.3037 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | adenoreceptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | g-protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | myosin xvIII | 0.0068 | 0.0551 | 0.1816 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.007 | 0.0578 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | orexin receptor type 2 | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | follicle stimulating hormone receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | sex peptide receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1169 | 0.3848 |
Echinococcus multilocularis | fmrfamide receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | opsin-like receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0107 | 0.1169 | 0.3848 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0226 | 0.3037 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0067 | 0.053 | 0.0864 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Dopamine receptor protein 1 | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0074 | 0.0655 | 0.2156 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Brugia malayi | neuropeptide F receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | g protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | sulfakinin receptor protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | biogenic amine receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0068 | 0.0551 | 0.0616 |
Echinococcus granulosus | allatostatin A receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Serotonin receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | amine GPCR | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0068 | 0.0551 | 0.1816 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0067 | 0.053 | 0.0864 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0067 | 0.053 | 0.0864 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | AKH receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | GnHR receptor homolog | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | opsin-like receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0081 | 0.0762 | 0.251 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0107 | 0.1169 | 0.3848 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | G-protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | g protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0169 | 0.2145 | 0.7061 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | allatostatin A receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0107 | 0.1169 | 0.1305 | |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Cation transporter family protein | 0.0107 | 0.1169 | 0.3848 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0603 | 0.8955 | 1 | |
Loa Loa (eye worm) | TYRA-2 protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0931 | 0.3067 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | G protein-coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | histamine h1 receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | serotonin receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | fmrfamide receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | biogenic amine receptor | 0.0068 | 0.0551 | 0.1816 |
Trypanosoma brucei | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0067 | 0.053 | 0.0864 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | RE15519p | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | orotate phosphoribosyltransferase | 0.0067 | 0.053 | 0.1747 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0068 | 0.0551 | 0.0616 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Dopamine receptor protein 2 | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Brugia malayi | Serotonin receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0074 | 0.0655 | 0.2156 |
Brugia malayi | ORL1-like opioid receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | G-protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | g protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | sex peptide receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | serotonin receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | amine GPCR | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | Melatonin receptor type 1A | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | orotate phosphoribosyltransferase family protein | 0.0067 | 0.053 | 0.1747 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | somatostatin receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Trypanosoma brucei | DNA topoisomerase IB, large subunit | 0.0169 | 0.2145 | 1 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | amine GPCR | 0.0068 | 0.0551 | 0.1816 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Schistosoma mansoni | biogenic amine receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0068 | 0.0551 | 0.1816 |
Leishmania major | DNA topoisomerase IB, large subunit | 0.0169 | 0.2145 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Echinococcus granulosus | neuropeptide s receptor | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | putative neuropeptide receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0169 | 0.2145 | 0.7061 |
Trypanosoma cruzi | DNA topoisomerase IB, large subunit, putative | 0.0169 | 0.2145 | 1 |
Echinococcus granulosus | uridine 5' monophosphate synthase | 0.0067 | 0.053 | 0.1747 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0074 | 0.0655 | 0.2156 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0068 | 0.0551 | 0.1816 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0068 | 0.0551 | 0.1816 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0068 | 0.0551 | 0.1816 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0068 | 0.0551 | 0.1816 |
Leishmania major | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative | 0.0067 | 0.053 | 0.0864 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0501 | 0.1648 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0068 | 0.0551 | 0.1816 |
Echinococcus multilocularis | uridine 5' monophosphate synthase | 0.0067 | 0.053 | 0.1747 |
Onchocerca volvulus | 0.0068 | 0.0551 | 0.0616 | |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0551 | 0.1816 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 1.9 uM | Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells | ChEMBL. | 8410981 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.