Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0209 | 0.8611 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.1923 | 0.2852 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0588 | 0.0553 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.008 | 0.2417 | 0.2807 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.1923 | 0.2852 |
Onchocerca volvulus | 0.008 | 0.2417 | 0.2389 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2417 | 0.2807 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.007 | 0.1923 | 0.2234 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.008 | 0.2417 | 0.2807 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.1923 | 0.1548 |
Brugia malayi | chromobox protein homolog 3 | 0.0039 | 0.0445 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0445 | 0.0516 |
Brugia malayi | hypothetical protein | 0.008 | 0.2417 | 0.2807 |
Trichomonas vaginalis | set domain proteins, putative | 0.0238 | 1 | 1 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.1923 | 0.2852 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2417 | 0.2807 |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.1431 | 0.1032 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1431 | 0.1661 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.1923 | 0.2852 |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0 | 0.5 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.1923 | 0.2852 |
Echinococcus granulosus | geminin | 0.017 | 0.6743 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1431 | 0.1661 |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.014 | 0.529 | 0.6143 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0037 | 0.0043 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0041 | 0.0551 | 0.0817 |
Onchocerca volvulus | 0.008 | 0.2417 | 0.2389 | |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.1923 | 0.1548 |
Brugia malayi | LBP/BPI | 0.006 | 0.1431 | 0.1661 |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.529 | 0.6143 |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0588 | 0.015 |
Brugia malayi | Pre-SET motif family protein | 0.0209 | 0.8611 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.6743 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.6743 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0588 | 0.015 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1431 | 0.1661 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.008 | 0.2417 | 0.2807 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0039 | 0.0445 | 0.0409 |
Brugia malayi | hypothetical protein | 0.008 | 0.2417 | 0.2807 |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.014 | 0.529 | 0.6143 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.008 | 0.2417 | 0.2807 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1431 | 0.1661 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.008 | 0.2417 | 0.2807 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.014 | 0.529 | 0.6143 |
Brugia malayi | hypothetical protein | 0.006 | 0.1431 | 0.1661 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2417 | 0.2807 |
Echinococcus multilocularis | geminin | 0.017 | 0.6743 | 1 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.014 | 0.529 | 0.6143 |
Onchocerca volvulus | 0.0041 | 0.0551 | 0.0516 | |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2417 | 0.2807 |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Brugia malayi | Heterochromatin protein 1 | 0.007 | 0.1923 | 0.2234 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.2417 | 0.2807 |
Onchocerca volvulus | 0.006 | 0.1431 | 0.1399 | |
Onchocerca volvulus | 0.014 | 0.529 | 0.5272 | |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.1923 | 0.2852 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.