Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0614 | 0.0099 | 0.0099 |
Brugia malayi | Sodium/calcium exchanger protein | 0.5146 | 0.3762 | 1 |
Onchocerca volvulus | Deterin homolog | 0.0614 | 0.0099 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.5146 | 0.3762 | 0.3762 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0614 | 0.0099 | 0.0099 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.2269 | 0.1437 | 0.5 |
Onchocerca volvulus | 0.0614 | 0.0099 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0614 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0614 | 0.0099 | 0.0099 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0614 | 0.0099 | 0.0099 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0614 | 0.0099 | 0.0263 |
Trichomonas vaginalis | alpha-L-fucosidase, putative | 0.2269 | 0.1437 | 0.5 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0614 | 0.0099 | 0.0099 |
Schistosoma mansoni | hypothetical protein | 0.0614 | 0.0099 | 0.0099 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0614 | 0.0099 | 0.0099 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0614 | 0.0099 | 0.0099 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0614 | 0.0099 | 0.0263 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.