Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | dual specificity | 0.0496 | 0.154 | 0.154 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0496 | 0.154 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0496 | 0.154 | 0.1479 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.1469 | 0.1469 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0496 | 0.154 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0496 | 0.154 | 0.5 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0338 | 0.0071 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0674 | 0.3191 | 0.3191 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0338 | 0.0071 | 0.5 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0338 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0674 | 0.3191 | 0.3191 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0496 | 0.154 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0496 | 0.154 | 0.5 |
Brugia malayi | hypothetical protein | 0.0674 | 0.3191 | 1 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0338 | 0.0071 | 0.0071 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0496 | 0.154 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0496 | 0.154 | 0.4709 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0496 | 0.154 | 0.154 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0338 | 0.0071 | 0.0071 |
Echinococcus granulosus | dual specificity | 0.0496 | 0.154 | 0.154 |
Giardia lamblia | Kinase, CMGC CLK | 0.0338 | 0.0071 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0496 | 0.154 | 0.5 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0496 | 0.154 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0488 | 0.1469 | 0.1469 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0338 | 0.0071 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0338 | 0.0071 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.