Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0848 | 0.6611 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0437 | 0.3357 | 0.0111 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0848 | 0.6611 | 1 |
Giardia lamblia | Kinase, AGC PKA | 0.0848 | 0.6611 | 0.5 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0437 | 0.3357 | 0.3357 |
Brugia malayi | Protein kinase domain containing protein | 0.0437 | 0.3357 | 0.3357 |
Echinococcus granulosus | nervana 2 | 0.0839 | 0.6537 | 0.977 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0839 | 0.6537 | 0.977 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0839 | 0.6537 | 0.977 |
Echinococcus granulosus | nervana 2 | 0.0839 | 0.6537 | 0.977 |
Trichomonas vaginalis | AGC family protein kinase | 0.0437 | 0.3357 | 0.0111 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0848 | 0.6611 | 1 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0848 | 0.6611 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0437 | 0.3357 | 0.3357 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0848 | 0.6611 | 0.4899 |
Trichomonas vaginalis | AGC family protein kinase | 0.0437 | 0.3357 | 0.0111 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0848 | 0.6611 | 1 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0839 | 0.6537 | 0.977 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0848 | 0.6611 | 1 |
Trypanosoma cruzi | Protein kinase B | 0.0848 | 0.6611 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0839 | 0.6537 | 0.977 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0848 | 0.6611 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0437 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0437 | 0.3357 | 0.3357 |
Trichomonas vaginalis | AGC family protein kinase | 0.0437 | 0.3357 | 0.0111 |
Brugia malayi | protein kinase C II. | 0.0437 | 0.3357 | 0.3357 |
Entamoeba histolytica | protein kinase 2, putative | 0.0848 | 0.6611 | 0.4899 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0437 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0437 | 0.3357 | 0.3357 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0848 | 0.6611 | 1 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0848 | 0.6611 | 1 |
Brugia malayi | Hr1 repeat family protein | 0.0437 | 0.3357 | 0.3357 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0848 | 0.6611 | 1 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0839 | 0.6537 | 0.977 |
Echinococcus multilocularis | nervana 2 | 0.0839 | 0.6537 | 0.977 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0437 | 0.3357 | 0.3357 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0437 | 0.3357 | 0.3357 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0848 | 0.6611 | 0.4899 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0848 | 0.6611 | 0.5 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 21470864 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.