Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | bromodomain-containing protein | 0.0105 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 1 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0146 | 0.3163 | 0.3163 |
Echinococcus multilocularis | bromodomain containing 2 | 0.0235 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0131 | 0.1964 | 0.1964 |
Entamoeba histolytica | bromodomain-containing protein | 0.0105 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0146 | 0.3163 | 0.3163 |
Entamoeba histolytica | bromodomain-containing protein | 0.0105 | 0 | 0.5 |
Trichomonas vaginalis | bromodomain containing protein, putative | 0.0146 | 0.3163 | 0.3163 |
Giardia lamblia | Kinase, putative | 0.0105 | 0 | 0.5 |
Toxoplasma gondii | bromodomain-containing protein | 0.0105 | 0 | 0.5 |
Echinococcus granulosus | bromodomain containing 2 | 0.0235 | 1 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0235 | 1 | 0.5 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0235 | 1 | 1 |
Schistosoma mansoni | bromodomain-containing protein 3 brd3 | 0.0235 | 1 | 0.5 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0235 | 1 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0146 | 0.3163 | 0.3163 |
Onchocerca volvulus | 0.0105 | 0 | 0.5 | |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0146 | 0.3163 | 0.3163 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.