Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0084 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0084 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0084 | 0.5 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0084 | 0.5 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0084 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0084 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0084 | 0.5 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0084 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Agonist activity at human recombinant P2Y4 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production at 10 uM after 30 mins by scintillation proximity assay | ChEMBL. | 21528910 | |
Activity (functional) | <= 50 % | Agonist activity at human recombinant P2Y2 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production at 10 uM after 30 mins by scintillation proximity assay | ChEMBL. | 21528910 |
Activity (functional) | <= 50 % | Agonist activity at human recombinant P2Y6 receptor expressed in human 1321N1 cells assessed as [3H]inositol phosphate production at 10 uM after 30 mins by scintillation proximity assay | ChEMBL. | 21528910 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.