Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0123 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0094 | 0.5667 | 0.5667 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0094 | 0.5667 | 0.5667 |
Echinococcus granulosus | caspase 2 | 0.0094 | 0.5667 | 0.5667 |
Echinococcus multilocularis | caspase 2 | 0.0094 | 0.5667 | 0.5667 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.5667 | 0.5667 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0123 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 1 | 1 |
Brugia malayi | Cell death protein 3 precursor | 0.0094 | 0.5667 | 0.5667 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0123 | 1 | 1 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0123 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.5667 | 0.5667 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0123 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 1 | 1 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0123 | 1 | 1 |
Onchocerca volvulus | Deterin homolog | 0.0123 | 1 | 1 |
Onchocerca volvulus | 0.0123 | 1 | 1 | |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0123 | 1 | 1 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0094 | 0.5667 | 0.5667 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0094 | 0.5667 | 0.5667 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.5667 | 0.5667 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.