Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein 70, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | Heat shock 70 kDa protein 4 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock kda protein | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein kDa heat shock kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein 4 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein 4 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | Heat Shock protein family member hsp 3 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | 0.0003 | 0 | 0.5 | |
Echinococcus multilocularis | Heat shock 70 kDa protein 4 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock 70 kDa protein 1 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein 70 (HSP70)-4, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein 70 family | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | 0.0003 | 0 | 0.5 | |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0095 | 0.267 | 1 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein 70kD, putative | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | Heat shock 70 kDa protein 4 | 0.0003 | 0 | 0.5 |
Brugia malayi | Telomerase reverse transcriptase | 0.0253 | 0.7245 | 1 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0095 | 0.267 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0003 | 0 | 0.5 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0095 | 0.267 | 1 |
Entamoeba histolytica | heat shock protein70, hsp70A2, putative | 0.0003 | 0 | 0.5 |
Giardia lamblia | Telomerase catalytic subunit | 0.0095 | 0.267 | 1 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0095 | 0.267 | 1 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0095 | 0.267 | 1 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0095 | 0.267 | 1 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 related | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein70, hsp70A2, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | microsomal stress 70 protein ATPase core precursor, putative | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein70, hsp70A2, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | Heat shock 70 kDa protein 4 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein 70 (HSP70)-4, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Loa Loa (eye worm) | heat shock 70kDa protein 5 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 related | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein 70 (HSP70)-4, putative | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 71 kDa protein | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein 70kD, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Schistosoma mansoni | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein 70, putative | 0.0003 | 0 | 0.5 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0095 | 0.267 | 1 |
Echinococcus multilocularis | heat shock 70 kDa protein 1A:1B | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock kda protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein kDa heat shock kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | 0.0003 | 0 | 0.5 | |
Echinococcus granulosus | heat shock protein 70b | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein kDa | 0.0003 | 0 | 0.5 |
Schistosoma mansoni | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein70, hsp70A2, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70b | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | 3'partial|5'partial|heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | Heat shock 70 kDa protein 4 | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | 70 kDa heat shock protein, putative | 0.0003 | 0 | 0.5 |
Schistosoma mansoni | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat shock 70 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein 70 family | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 related | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein 70, putative | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | Heat Shock protein family member (hsp 3) | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 71 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock 70 kda protein 1a | 0.0003 | 0 | 0.5 |
Echinococcus multilocularis | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Entamoeba histolytica | heat shock protein 70, putative | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 70 | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 71 kDa protein | 0.0003 | 0 | 0.5 |
Echinococcus granulosus | heat shock protein 71 kDa protein | 0.0003 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 50.1187 uM | PubChem BioAssay. qHTS for Small Molecule Inhibitors of the ERG Ets/DNA interaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.