Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | prolyl endopeptidase | 0.2961 | 0.7424 | 0.6691 |
Trypanosoma cruzi | prolyl endopeptidase | 0.2961 | 0.7424 | 1 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.2961 | 0.7424 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2961 | 0.7424 | 0.7424 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.2402 | 0.5407 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1516 | 0.2216 | 0.1059 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.2961 | 0.7424 | 0.6691 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.3676 | 1 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.2961 | 0.7424 | 0.6691 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.3676 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1516 | 0.2216 | 0.1059 |
Brugia malayi | prolyl oligopeptidase family protein | 0.2961 | 0.7424 | 0.7424 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.3676 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1516 | 0.2216 | 0.2216 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1516 | 0.2216 | 0.1059 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.3676 | 1 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.1345 | 0.1599 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.2961 | 0.7424 | 0.6691 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1516 | 0.2216 | 0.1059 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.3676 | 1 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1516 | 0.2216 | 0.1059 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.1345 | 0.1599 | 0.5 |
Toxoplasma gondii | prolyl endopeptidase | 0.2961 | 0.7424 | 1 |
Trypanosoma brucei | prolyl endopeptidase | 0.2961 | 0.7424 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.