Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | CMGC/CK2 protein kinase | 0.0772 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CK2 | 0.0772 | 1 | 0.5 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0772 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0772 | 1 | 0.5 |
Plasmodium vivax | unspecified product | 0.0772 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0772 | 1 | 0.5 |
Echinococcus multilocularis | casein kinase ii subunit alpha | 0.0772 | 1 | 1 |
Trypanosoma brucei | Casein kinase II | 0.0772 | 1 | 1 |
Onchocerca volvulus | 0.0248 | 0.314 | 0.5 | |
Toxoplasma gondii | CMGC kinase, CK2 family | 0.0772 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0772 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0772 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0772 | 1 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0772 | 1 | 0.5 |
Trypanosoma cruzi | casein kinase II, putative | 0.0772 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0772 | 1 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0772 | 1 | 0.5 |
Plasmodium falciparum | casein kinase 2, alpha subunit | 0.0772 | 1 | 0.5 |
Echinococcus granulosus | casein kinase ii subunit alpha | 0.0772 | 1 | 0.5 |
Plasmodium vivax | casein kinase 2, alpha subunit, putative | 0.0772 | 1 | 0.5 |
Entamoeba histolytica | casein kinase, putative | 0.0772 | 1 | 0.5 |
Leishmania major | casein kinase II, putative | 0.0772 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.