Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.4427 | 0.5 | 0.5 |
Echinococcus granulosus | arginase 2 mitochondrial | 0.4427 | 0.5 | 0.5 |
Plasmodium falciparum | arginase | 0.4427 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.4427 | 0.5 | 0.5 |
Entamoeba histolytica | Arginase, putative | 0.4427 | 0.5 | 0.5 |
Echinococcus multilocularis | 0.4427 | 0.5 | 0.5 | |
Echinococcus multilocularis | arginase 2, mitochondrial | 0.4427 | 0.5 | 0.5 |
Trichomonas vaginalis | Arginase, putative | 0.4427 | 0.5 | 0.5 |
Leishmania major | arginase | 0.4427 | 0.5 | 0.5 |
Schistosoma mansoni | arginase | 0.4427 | 0.5 | 0.5 |
Plasmodium vivax | arginase, putative | 0.4427 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 500 uM | Inhibitory concentration of the compound against KDO 8-P synthase | ChEMBL. | 11597402 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.