Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0278 | 0.9791 | 0.9791 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0278 | 0.9791 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0633 | 0.0647 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0633 | 0.0633 |
Echinococcus granulosus | geminin | 0.017 | 0.5434 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.5434 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0633 | 0.0633 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0278 | 0.9791 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0633 | 0.0647 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0103 | 0.2777 | 0.5111 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1035 | 0.1057 |
Onchocerca volvulus | 0.0278 | 0.9791 | 0.5 | |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0278 | 0.9791 | 0.5 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3445 | 0.3519 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Echinococcus multilocularis | geminin | 0.017 | 0.5434 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.5434 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0278 | 0.9791 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.759 | 0.7752 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0278 | 0.9791 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.