Detailed information for compound 157279

Basic information

Technical information
  • TDR Targets ID: 157279
  • Name: N-(7-chloro-6-oxoheptyl)-4-methylbenzenesulfo namide
  • MW: 317.832 | Formula: C14H20ClNO3S
  • H donors: 1 H acceptors: 3 LogP: 2.6 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: ClCC(=O)CCCCCNS(=O)(=O)c1ccc(cc1)C
  • InChi: 1S/C14H20ClNO3S/c1-12-6-8-14(9-7-12)20(18,19)16-10-4-2-3-5-13(17)11-15/h6-9,16H,2-5,10-11H2,1H3
  • InChiKey: APAHKELLCHULLY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(7-chloro-6-oxo-heptyl)-4-methyl-benzenesulfonamide
  • N-(7-chloro-6-keto-heptyl)-4-methyl-benzenesulfonamide
  • 72676-79-0
  • 6-(N-Tosyl)aminocaproic acid chloromethyl ketone
  • BRN 5589118
  • Benzenesulfonamide, N-(7-chloro-6-oxoheptyl)-4-methyl-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi RE15519p 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus g protein coupled receptor 0.005 0.4684 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.4684 1
Echinococcus multilocularis dro:myosuppressin receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.4684 0.4684
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni histamine h1 receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.0071 1 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Onchocerca volvulus 0.0071 1 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni amine GPCR 0.005 0.4684 0.4684
Schistosoma mansoni neuropeptide receptor 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.4684 1
Schistosoma mansoni biogenic amine receptor 0.005 0.4684 0.4684
Brugia malayi putative neuropeptide receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.4684 0.4684
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Schistosoma mansoni neuropeptide receptor 0.005 0.4684 0.4684
Schistosoma mansoni alpha-1 adrenergic receptor 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Echinococcus granulosus neuropeptide receptor 0.005 0.4684 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.005 0.4684 0.4684
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.4684 1
Echinococcus multilocularis G protein coupled receptor 139 0.005 0.4684 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.005 0.4684 0.4684
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.4684 1
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Echinococcus granulosus 7tm_1 domain containing protein 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis neuropeptide s receptor 0.005 0.4684 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Echinococcus granulosus neuropeptide s receptor 0.005 0.4684 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Brugia malayi Serotonin receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus g protein coupled receptor 0.005 0.4684 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.005 0.4684 0.4684
Onchocerca volvulus Neuropeptide F receptor homolog 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus G protein coupled receptor 139 0.005 0.4684 1
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus neuropeptide FF receptor 2 0.005 0.4684 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus neuropeptide Y receptor 0.005 0.4684 1
Brugia malayi Dopamine receptor protein 2 0.005 0.4684 0.4684
Echinococcus multilocularis g-protein coupled receptor 0.005 0.4684 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus neuropeptide receptor 0.005 0.4684 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.005 0.4684 0.4684
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.4684 1
Echinococcus granulosus neuropeptides capa receptor 0.005 0.4684 1
Echinococcus granulosus neuropeptide Y receptor 0.005 0.4684 1
Brugia malayi sulfakinin receptor protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni growth hormone secretagogue receptor 0.005 0.4684 0.4684
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.005 0.4684 0.4684
Schistosoma mansoni amine GPCR 0.005 0.4684 0.4684
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni amine GPCR 0.005 0.4684 0.4684
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.4684 1
Echinococcus multilocularis neuropeptide receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Schistosoma mansoni hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis somatostatin receptor 0.005 0.4684 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis neuropeptide receptor A26 0.005 0.4684 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.4684 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Brugia malayi G protein-coupled receptor 0.005 0.4684 0.4684
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.4684 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.005 0.4684 1
Echinococcus granulosus dro:myosuppressin receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.4684 1
Onchocerca volvulus 0.005 0.4684 0.4684
Schistosoma mansoni hypothetical protein 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Echinococcus multilocularis sex peptide receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Echinococcus granulosus hypothetical protein 0.005 0.4684 1
Brugia malayi putative neuropeptide receptor NPR1 0.005 0.4684 0.4684
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.4684 0.4684
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.005 0.4684 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.005 0.4684 1
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.4684 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.005 0.4684 0.4684
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.4684 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.005 0.4684 0.4684
Brugia malayi Dopamine receptor protein 1 0.005 0.4684 0.4684
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.4684 1
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Echinococcus granulosus sex peptide receptor 0.005 0.4684 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.4684 1
Echinococcus granulosus somatostatin receptor 0.005 0.4684 1
Echinococcus multilocularis g protein coupled receptor 0.005 0.4684 1
Schistosoma mansoni biogenic amine receptor 0.005 0.4684 0.4684
Echinococcus multilocularis serotonin receptor 0.005 0.4684 1
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.4684 1
Brugia malayi neuropeptide F receptor 0.005 0.4684 0.4684
Schistosoma mansoni opsin-like receptor 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis neuropeptide receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Brugia malayi neuropeptide F receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) TYRA-2 protein 0.005 0.4684 0.4684
Echinococcus multilocularis fmrfamide receptor 0.005 0.4684 1
Schistosoma mansoni amine GPCR 0.005 0.4684 0.4684
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.4684 0.4684
Echinococcus granulosus tachykinin peptides receptor 99D 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni neuropeptide receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.4684 0.4684
Brugia malayi Dopamine receptor 0.005 0.4684 0.4684
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.005 0.4684 1
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.4684 1
Onchocerca volvulus 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Brugia malayi AKH receptor 0.005 0.4684 0.4684
Brugia malayi Melatonin receptor type 1A 0.005 0.4684 0.4684
Echinococcus granulosus thyrotropin releasing hormone receptor 0.005 0.4684 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni myosin xvIII 0.005 0.4684 0.4684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Echinococcus multilocularis g protein coupled receptor 0.005 0.4684 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.005 0.4684 0.4684
Echinococcus granulosus allatostatin A receptor 0.005 0.4684 1
Schistosoma mansoni neuropeptide f receptor 76f 0.005 0.4684 0.4684
Schistosoma mansoni hypothetical protein 0.0071 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Echinococcus granulosus alpha 1A adrenergic receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.4684 0.4684
Echinococcus multilocularis orexin receptor type 2 0.005 0.4684 1
Echinococcus granulosus neuropeptide receptor A26 0.005 0.4684 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.005 0.4684 0.4684
Onchocerca volvulus 0.005 0.4684 0.4684
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.005 0.4684 1
Schistosoma mansoni amine GPCR 0.005 0.4684 0.4684
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.005 0.4684 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.4684 0.4684
Echinococcus granulosus serotonin receptor 0.005 0.4684 1
Schistosoma mansoni neuropeptide receptor 0.005 0.4684 0.4684
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.005 0.4684 1
Schistosoma mansoni hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Echinococcus multilocularis tachykinin peptides receptor 99D 0.005 0.4684 1
Onchocerca volvulus 0.005 0.4684 0.4684
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.005 0.4684 1
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis fmrfamide receptor 0.005 0.4684 1
Echinococcus multilocularis g protein coupled receptor 0.005 0.4684 1
Loa Loa (eye worm) melatonin receptor type 1A 0.005 0.4684 0.4684
Echinococcus multilocularis neuropeptide FF receptor 2 0.005 0.4684 1
Brugia malayi G-protein coupled receptor 0.005 0.4684 0.4684
Schistosoma mansoni hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.005 0.4684 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.4684 0.4684
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.4684 1
Echinococcus granulosus neuropeptides capa receptor 0.005 0.4684 1
Schistosoma mansoni opsin-like receptor 0.005 0.4684 0.4684
Brugia malayi ORL1-like opioid receptor 0.005 0.4684 0.4684
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.005 0.4684 0.4684
Brugia malayi follicle stimulating hormone receptor 0.005 0.4684 0.4684
Brugia malayi Serotonin receptor 0.005 0.4684 0.4684
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.005 0.4684 0.4684
Echinococcus granulosus g protein coupled receptor 0.005 0.4684 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.005 0.4684 1
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.4684 1
Schistosoma mansoni biogenic amine receptor 0.005 0.4684 0.4684
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.4684 1
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.4684 1
Onchocerca volvulus 0.005 0.4684 0.4684
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.005 0.4684 0.4684
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.4684 1
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.4684 1
Schistosoma mansoni opsin-like receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Brugia malayi G protein-coupled receptor F59B2.13 0.005 0.4684 0.4684
Brugia malayi larval opioid receptor 0.005 0.4684 0.4684
Echinococcus multilocularis allatostatin A receptor 0.005 0.4684 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.005 0.4684 0.4684
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.4684 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Schistosoma mansoni adenoreceptor 0.005 0.4684 0.4684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.4684 0.4684
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.4684 0.4684
Brugia malayi Tachykinin-like peptides receptor 99D 0.005 0.4684 0.4684
Echinococcus multilocularis biogenic amine (5HT) receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus granulosus fmrfamide receptor 0.005 0.4684 1
Brugia malayi GnHR receptor homolog 0.005 0.4684 0.4684
Brugia malayi Serotonin/octopamine receptor family protein 7 0.005 0.4684 0.4684
Echinococcus granulosus g-protein coupled receptor 0.005 0.4684 1
Brugia malayi hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis serotonin receptor 0.005 0.4684 1
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Brugia malayi G-protein coupled receptor 0.005 0.4684 0.4684
Echinococcus granulosus orexin receptor type 2 0.005 0.4684 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.005 0.4684 1
Onchocerca volvulus 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Loa Loa (eye worm) follicle stimulating hormone receptor 0.005 0.4684 0.4684
Loa Loa (eye worm) hypothetical protein 0.005 0.4684 0.4684
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.005 0.4684 1

Activities

Activity type Activity value Assay description Source Reference
ascrit (functional) = 0.01 Screening of Ehrlich ascites carcinoma cells in mice at 20 mg/kg/day intraperitoneally. ChEMBL. 7365742
Inhibition (functional) = 99.9 % Percentage inhibition as antitumor activity in carcinoma CF1 male mice. ChEMBL. 7365742
Inhibition (functional) = 99.9 % Percentage inhibition as antitumor activity in carcinoma CF1 male mice. ChEMBL. 7365742
Survival (functional) = 11.2 day Survival of the mice for average number of days; expressed as average survival days ChEMBL. 7365742
Survival (functional) = 11.2 day Survival of the mice for average number of days; expressed as average survival days ChEMBL. 7365742
Survival after 10 days (functional) = 5 Anticarcinoma activity of Diazomethyl Ketone against Ehrlich ascites Carcinoma pharmacological screens were reported; 5/6 ChEMBL. 7365742
T/C (functional) = 116 T/C expresses antileukemic activity measured as tested over that of control. ChEMBL. 7365742
Volume of ascrit fluid (functional) = 0.02 Volume of fluid collected 8 days after tumor transplantation in mice. ChEMBL. 7365742

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.