Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Echinococcus multilocularis | cathepsin b | 0.0291 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0054 | 0 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0054 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0105 | 0.2134 | 0.2134 |
Onchocerca volvulus | Cathepsin F homolog | 0.0054 | 0 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0054 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0054 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0291 | 1 | 1 |
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0105 | 0.2134 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0105 | 0.2134 | 0.2134 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0054 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0105 | 0.2134 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0105 | 0.2134 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0054 | 0 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0105 | 0.2134 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0291 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0291 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0291 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0105 | 0.2134 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0291 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0105 | 0.2134 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0054 | 0 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0054 | 0 | 0.5 |
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0054 | 0 | 0.5 |
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Plasmodium vivax | vivapain-2 | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | cathepsin B | 0.0105 | 0.2134 | 0.2134 |
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0291 | 1 | 1 |
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0291 | 1 | 1 |
Onchocerca volvulus | 0.0054 | 0 | 0.5 | |
Giardia lamblia | Cathepsin B precursor | 0.0105 | 0.2134 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0291 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0054 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.