Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0331 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0331 | 1 | 1 |
Echinococcus multilocularis | insulin receptor | 0.0097 | 0.0129 | 0.0129 |
Schistosoma mansoni | tyrosine kinase | 0.0164 | 0.2932 | 0.284 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0331 | 1 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0304 | 0.8889 | 0.8875 |
Schistosoma mansoni | tyrosine kinase | 0.0162 | 0.2859 | 0.2766 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0331 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0331 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0164 | 0.2932 | 0.284 |
Echinococcus granulosus | carboxylesterase 5A | 0.0331 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0162 | 0.2859 | 0.2766 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0097 | 0.0129 | 0.0129 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0304 | 0.8889 | 0.8875 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0331 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0331 | 1 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0164 | 0.2932 | 0.2932 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0304 | 0.8889 | 0.8875 |
Loa Loa (eye worm) | carboxylesterase | 0.0331 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0164 | 0.2932 | 0.284 |
Schistosoma mansoni | tyrosine kinase | 0.0304 | 0.8889 | 0.8875 |
Brugia malayi | Carboxylesterase family protein | 0.0331 | 1 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0304 | 0.8889 | 0.8889 |
Schistosoma mansoni | tyrosine kinase | 0.0162 | 0.2859 | 0.2766 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0164 | 0.2932 | 0.284 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.