Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | kinesin-like protein KLP2 | 0.0166 | 0.1223 | 1 |
Echinococcus multilocularis | kinesin family 1 | 0.1281 | 1 | 1 |
Brugia malayi | Kinesin motor domain containing protein | 0.0166 | 0.1223 | 1 |
Plasmodium falciparum | kinesin-5 | 0.0166 | 0.1223 | 0.5 |
Entamoeba histolytica | kinesin, putative | 0.0166 | 0.1223 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.1115 | 0.869 | 1 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0166 | 0.1223 | 0.5 |
Plasmodium vivax | kinesin-5 | 0.0166 | 0.1223 | 0.5 |
Giardia lamblia | Kinesin-5 | 0.0166 | 0.1223 | 0.5 |
Schistosoma mansoni | kinesin eg-5 | 0.0166 | 0.1223 | 0.1408 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.