Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0744 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0171 | 0.0651 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.4708 | 0.4708 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0744 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Onchocerca volvulus | 0.042 | 0.4708 | 0.4708 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.042 | 0.4708 | 0.4708 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0744 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0171 | 0.0651 | 0.5 |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0171 | 0.0651 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0744 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0131 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0744 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0171 | 0.0651 | 0.5 |
Onchocerca volvulus | 0.0289 | 0.257 | 0.257 | |
Giardia lamblia | NADPH oxidoreductase, putative | 0.0171 | 0.0651 | 0.5 |
Toxoplasma gondii | kringle domain-containing protein | 0.0744 | 1 | 0.5 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0744 | 1 | 1 |
Trichomonas vaginalis | NAD(P)H dehydrogenase, putative | 0.0171 | 0.0651 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0171 | 0.0651 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.042 | 0.4708 | 0.4708 |
Brugia malayi | Trypsin family protein | 0.042 | 0.4708 | 0.4708 |
Brugia malayi | Kringle domain containing protein | 0.0744 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.042 | 0.4708 | 0.4708 |
Onchocerca volvulus | 0.0744 | 1 | 1 | |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0744 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0744 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0744 | 1 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 19555126 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.