Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | egf-like domain protein | 0.0117 | 0.4505 | 0.4505 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0117 | 0.4505 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0117 | 0.4505 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.098 | 0.2177 |
Giardia lamblia | High cysteine protein | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.4505 | 1 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0117 | 0.4505 | 0.4505 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0.0006 | 0.5 |
Echinococcus multilocularis | laminin | 0.0117 | 0.4505 | 0.4505 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0045 | 0.0006 | 0.5 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0045 | 0.0006 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.098 | 0.2177 |
Echinococcus granulosus | Tolloid protein 1 | 0.0117 | 0.4505 | 0.4505 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0006 | 0.5 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0117 | 0.4505 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0006 | 0.5 |
Brugia malayi | Inositol-1 | 0.0045 | 0.0006 | 0.0014 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0045 | 0.0006 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0045 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.4505 | 1 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0045 | 0.0006 | 0.5 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0117 | 0.4505 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0045 | 0.0006 | 0.0006 |
Echinococcus multilocularis | geminin | 0.0205 | 1 | 1 |
Echinococcus multilocularis | fibrillin 1 | 0.0117 | 0.4505 | 0.4505 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.4505 | 1 |
Toxoplasma gondii | calcium binding egf domain-containing protein | 0.0117 | 0.4505 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0045 | 0.0006 | 0.0014 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0117 | 0.4505 | 0.4505 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0006 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.098 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.4505 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0045 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0117 | 0.4505 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0045 | 0.0006 | 0.0014 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0045 | 0.0006 | 0.0006 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.098 | 0.2177 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.0006 | 0.5 |
Onchocerca volvulus | Arrow homolog | 0.0117 | 0.4505 | 1 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0117 | 0.4505 | 1 |
Echinococcus granulosus | laminin | 0.0117 | 0.4505 | 0.4505 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Brugia malayi | Fibulin-1 precursor | 0.0117 | 0.4505 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0.0006 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.4505 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.