Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.1237 | 0.142 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1237 | 0.1237 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.1237 | 0.142 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0051 | 0.0332 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0129 | 0.6938 | 0.7968 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.1237 | 0.1237 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0129 | 0.6938 | 0.6938 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.1237 | 0.142 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0051 | 0.0332 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0149 | 0.8707 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0129 | 0.6938 | 0.7968 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1237 | 0.1237 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0129 | 0.6938 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0129 | 0.6938 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.1237 | 0.1237 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0129 | 0.6938 | 1 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0115 | 0.5787 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.8707 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0129 | 0.6938 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0149 | 0.8707 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.1237 | 0.142 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0129 | 0.6938 | 0.6938 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.4677 | 0.4677 |
Echinococcus granulosus | prolyl endopeptidase | 0.0129 | 0.6938 | 0.6938 |
Trypanosoma brucei | prolyl endopeptidase | 0.0129 | 0.6938 | 1 |
Brugia malayi | RNA binding protein | 0.0062 | 0.1237 | 0.142 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0102 | 0.4677 | 0.5371 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.1237 | 0.142 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1237 | 0.1237 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1237 | 0.1237 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0129 | 0.6938 | 0.6938 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.1237 | 0.1237 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0149 | 0.8707 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.4677 | 0.5371 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.