Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0616 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.021 | 0.2499 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.021 | 0.2499 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.021 | 0.2499 | 0.5 |
Plasmodium vivax | PST-A protein | 0.021 | 0.2499 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0616 | 1 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0616 | 1 | 1 |
Mycobacterium tuberculosis | Possible lysophospholipase | 0.021 | 0.2499 | 0.3543 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0074 | 0 | 0.5 |
Plasmodium falciparum | lysophospholipase, putative | 0.021 | 0.2499 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.021 | 0.2499 | 1 |
Plasmodium falciparum | esterase, putative | 0.021 | 0.2499 | 1 |
Mycobacterium ulcerans | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD | 0.0464 | 0.7191 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0616 | 1 | 1 |
Schistosoma mansoni | amidase | 0.0616 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0616 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.021 | 0.2499 | 0.5 |
Mycobacterium tuberculosis | 4,9-DHSA hydrolase | 0.0456 | 0.7053 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.021 | 0.2499 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.021 | 0.2499 | 0.5 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.021 | 0.2499 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.021 | 0.2499 | 0.3475 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.021 | 0.2499 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.021 | 0.2499 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0616 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.021 | 0.2499 | 0.5 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.021 | 0.2499 | 1 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0074 | 0 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.021 | 0.2499 | 0.5 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0074 | 0 | 0.5 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.021 | 0.2499 | 0.5 |
Mycobacterium leprae | POSSIBLE LYSOPHOSPHOLIPASE | 0.021 | 0.2499 | 1 |
Leishmania major | monoglyceride lipase, putative | 0.021 | 0.2499 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.021 | 0.2499 | 0.5 |
Mycobacterium ulcerans | lysophospholipase | 0.021 | 0.2499 | 0.3475 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.