Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cannabinoid receptor 1 (brain) | Starlite/ChEMBL | References |
Homo sapiens | cannabinoid receptor 2 (macrophage) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (medium chain) | 0.0566 | 0.1813 | 0.5229 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.079 | 0.3468 | 0.5951 |
Trichomonas vaginalis | aldehyde oxidase, putative | 0.1675 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable carbon monoxyde dehydrogenase (large chain) | 0.079 | 0.3468 | 1 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 | 0.0566 | 0.1813 | 0.3111 |
Mycobacterium ulcerans | aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 | 0.079 | 0.3468 | 0.5951 |
Mycobacterium ulcerans | carbon monoxide dehydrogenase | 0.111 | 0.5827 | 1 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase large chain CoxL | 0.0497 | 0.1304 | 0.2238 |
Mycobacterium ulcerans | carbon monoxyde dehydrogenase medium chain CoxM | 0.0566 | 0.1813 | 0.3111 |
Trichomonas vaginalis | xanthine dehydrogenase, putative | 0.1675 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.