Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0085 | 0.1095 | 0.1095 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0085 | 0.1095 | 0.1095 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Onchocerca volvulus | 0.0682 | 1 | 0.5 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0373 | 0.5 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0682 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0682 | 1 | 0.5 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0085 | 0.1095 | 0.1095 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Echinococcus granulosus | enteropeptidase | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0335 | 0.0335 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.0464 | 0.0464 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.256 | 0.256 |
Loa Loa (eye worm) | hypothetical protein | 0.0268 | 0.3822 | 0.3822 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0085 | 0.1095 | 0.1095 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0039 | 0.0411 | 0.0411 |
Brugia malayi | Trypsin family protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0085 | 0.1095 | 0.1095 |
Echinococcus granulosus | Mastin | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0085 | 0.1095 | 0.1095 |
Brugia malayi | hypothetical protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.1095 | 0.1095 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0682 | 1 | 1 |
Onchocerca volvulus | 0.0682 | 1 | 0.5 | |
Echinococcus multilocularis | Mastin | 0.0682 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.1095 | 0.1095 |
Echinococcus multilocularis | GPCR, family 2 | 0.0085 | 0.1095 | 0.1095 |
Onchocerca volvulus | 0.0682 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0682 | 1 | 1 |
Echinococcus multilocularis | enteropeptidase | 0.0682 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0039 | 0.0411 | 0.0411 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.1095 | 0.1095 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0085 | 0.1095 | 0.1095 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0682 | 1 | 1 |
Onchocerca volvulus | 0.0682 | 1 | 0.5 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0085 | 0.1095 | 0.1095 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0268 | 0.3822 | 0.3822 |
Loa Loa (eye worm) | hypothetical protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1095 | 0.1095 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0682 | 1 | 1 |
Onchocerca volvulus | 0.0682 | 1 | 0.5 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0268 | 0.3822 | 0.3822 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0268 | 0.3822 | 0.3822 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0039 | 0.0411 | 0.0411 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0373 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0039 | 0.0411 | 0.0411 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.1095 | 0.1095 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0682 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0682 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0682 | 1 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0682 | 1 | 1 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | trypsin family protein | 0.0682 | 1 | 1 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0682 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0042 | 0.0464 | 0.0464 |
Schistosoma mansoni | hypothetical protein | 0.0183 | 0.256 | 0.256 |
Loa Loa (eye worm) | hypothetical protein | 0.0682 | 1 | 1 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0682 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0682 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0682 | 1 | 1 |
Onchocerca volvulus | 0.0682 | 1 | 0.5 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0183 | 0.256 | 0.256 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.