Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.2353 | 1 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2353 | 1 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0257 | 0.0117 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.2353 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0257 | 0.0117 | 0.0117 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0257 | 0.0117 | 0.0117 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0257 | 0.0117 | 0.0117 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.2353 | 1 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0257 | 0.0117 | 0.0117 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.2353 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0257 | 0.0117 | 0.0117 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0257 | 0.0117 | 0.0117 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2353 | 1 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2353 | 1 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0257 | 0.0117 | 0.0117 |
Schistosoma mansoni | thyroid hormone receptor | 0.0257 | 0.0117 | 0.0117 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2353 | 1 | 0.5 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.212 | 0.8903 | 0.889 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0257 | 0.0117 | 0.0117 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2353 | 1 | 0.5 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2353 | 1 | 0.5 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.212 | 0.8903 | 0.889 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0257 | 0.0117 | 0.0117 |
Schistosoma mansoni | thyroid hormone receptor | 0.0257 | 0.0117 | 0.0117 |
Schistosoma mansoni | nuclear hormone receptor | 0.0257 | 0.0117 | 0.0117 |
Echinococcus multilocularis | lysosomal protective protein | 0.2353 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2353 | 1 | 0.5 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.2353 | 1 | 1 |
Echinococcus granulosus | lysosomal protective protein | 0.2353 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.