Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0268 | 0.0933 | 0.0933 |
Brugia malayi | Animal haem peroxidase family protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Brugia malayi | Animal haem peroxidase family protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0268 | 0.0933 | 0.0933 |
Onchocerca volvulus | Peroxidase homolog | 0.043 | 0.2717 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.043 | 0.2717 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Brugia malayi | Peroxidasin | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.1091 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Brugia malayi | Animal haem peroxidase family protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | animal heme peroxidase | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | animal heme peroxidase | 0.043 | 0.2717 | 0.2717 |
Brugia malayi | Blistered cuticle protein 3 | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Onchocerca volvulus | 0.043 | 0.2717 | 0.5 | |
Onchocerca volvulus | 0.043 | 0.2717 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Onchocerca volvulus | Peroxidasin homolog | 0.043 | 0.2717 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.043 | 0.2717 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.043 | 0.2717 | 0.5 |
Loa Loa (eye worm) | animal heme peroxidase | 0.043 | 0.2717 | 0.2717 |
Brugia malayi | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Onchocerca volvulus | 0.043 | 0.2717 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.043 | 0.2717 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0908 | 0.7985 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.043 | 0.2717 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.043 | 0.2717 | 0.2717 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0908 | 0.7985 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.043 | 0.2717 | 0.2717 |
Brugia malayi | Animal haem peroxidase family protein | 0.043 | 0.2717 | 0.2717 |
Schistosoma mansoni | peroxidasin | 0.043 | 0.2717 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.2717 | 0.2717 |
Loa Loa (eye worm) | animal heme peroxidase | 0.043 | 0.2717 | 0.2717 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 14.1254 uM | PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.