Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0299 | 0.1374 | 1 |
Trichomonas vaginalis | serine threonine-protein kinase, putative | 0.0952 | 0.4962 | 1 |
Onchocerca volvulus | 0.0453 | 0.2222 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.2222 | 0.2222 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.0293 | 0.0544 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.0293 | 0.0544 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.1114 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0206 | 0.0861 | 0.0861 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0299 | 0.1374 | 0.5 |
Loa Loa (eye worm) | runx1 | 0.0057 | 0.0042 | 0.0042 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0063 | 0.0064 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0103 | 0.0293 | 0.0527 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0103 | 0.0293 | 0.0231 |
Brugia malayi | hypothetical protein | 0.0453 | 0.2222 | 0.2222 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0063 | 0.0022 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0952 | 0.4962 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.0293 | 0.0544 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0146 | 0.0532 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.0293 | 0.0544 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0063 | 0.0064 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.0293 | 0.0544 |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.1017 | 0.2011 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0103 | 0.0293 | 0.0293 |
Brugia malayi | Pre-SET motif family protein | 0.0206 | 0.0861 | 0.0861 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0103 | 0.0293 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0958 | 0.4996 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0103 | 0.0293 | 0.0293 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.0293 | 0.0544 |
Onchocerca volvulus | 0.0234 | 0.1017 | 0.3755 | |
Trichomonas vaginalis | CAMK family protein kinase | 0.0103 | 0.0293 | 0.0544 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.1114 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0103 | 0.0293 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0063 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0146 | 0.0532 | 0.5 |
Trypanosoma brucei | polo-like protein kinase | 0.0103 | 0.0293 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0146 | 0.0532 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.2222 | 0.2222 |
Schistosoma mansoni | lozenge | 0.0057 | 0.0042 | 0.0021 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0103 | 0.0293 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0103 | 0.0293 | 0.0252 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0299 | 0.1374 | 0.2733 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.