Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.2016 | 1 | 1 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2016 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2016 | 1 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0854 | 0.0495 | 0.0495 |
Echinococcus granulosus | lysosomal protective protein | 0.2016 | 1 | 1 |
Echinococcus granulosus | insulin receptor | 0.1822 | 0.8415 | 0.8332 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.2016 | 1 | 0.5 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.2016 | 1 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0968 | 0.1428 | 0.0981 |
Schistosoma mansoni | tyrosine kinase | 0.0854 | 0.0495 | 0.0495 |
Schistosoma mansoni | tyrosine kinase | 0.1822 | 0.8415 | 0.8415 |
Schistosoma mansoni | tyrosine kinase | 0.0854 | 0.0495 | 0.0495 |
Brugia malayi | Protein kinase domain containing protein | 0.1822 | 0.8415 | 0.8332 |
Echinococcus multilocularis | insulin receptor | 0.1822 | 0.8415 | 0.8332 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.1822 | 0.8415 | 0.8332 |
Brugia malayi | Protein kinase domain containing protein | 0.1028 | 0.1923 | 0.1503 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2016 | 1 | 0.5 |
Echinococcus multilocularis | lysosomal protective protein | 0.2016 | 1 | 1 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.1816 | 0.837 | 0.8285 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.2016 | 1 | 0.5 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.1822 | 0.8415 | 0.8332 |
Schistosoma mansoni | tyrosine kinase | 0.1822 | 0.8415 | 0.8415 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.2016 | 1 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.2016 | 1 | 0.5 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.1816 | 0.837 | 0.8285 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.1822 | 0.8415 | 0.8332 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.