Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase, putative | 0.0087 | 0.0276 | 0.4871 |
Trichomonas vaginalis | AGC family protein kinase | 0.0117 | 0.0552 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1155 | 1 | 1 |
Schistosoma mansoni | lysosomal protective protein precursor (cathepsin A) (carboxypeptidase | 0.0114 | 0.0526 | 0.0512 |
Toxoplasma gondii | aurora kinase | 0.0117 | 0.0552 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0117 | 0.0552 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0117 | 0.0552 | 0.0284 |
Entamoeba histolytica | protein kinase , putative | 0.0117 | 0.0552 | 1 |
Echinococcus granulosus | lysosomal protective protein | 0.1155 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1155 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0117 | 0.0552 | 0.0538 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0058 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | AUR protein kinase | 0.0117 | 0.0552 | 0.0284 |
Brugia malayi | serine/threonine kinase 12 | 0.0117 | 0.0552 | 0.0284 |
Trichomonas vaginalis | AGC family protein kinase | 0.0117 | 0.0552 | 1 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0117 | 0.0552 | 0.0538 |
Giardia lamblia | Aurora kinase | 0.0117 | 0.0552 | 1 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0117 | 0.0552 | 1 |
Trypanosoma brucei | aurora B kinase | 0.0117 | 0.0552 | 0.0284 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0117 | 0.0552 | 1 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0117 | 0.0552 | 1 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.1155 | 1 | 1 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.1155 | 1 | 1 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.1155 | 1 | 1 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.1155 | 1 | 0.5 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.1155 | 1 | 1 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.1041 | 0.8961 | 0.8961 |
Echinococcus multilocularis | aurora kinase A | 0.0117 | 0.0552 | 0.0552 |
Echinococcus granulosus | aurora kinase A | 0.0117 | 0.0552 | 0.0552 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0058 | 0.0014 | 0.0014 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1155 | 1 | 1 |
Echinococcus multilocularis | lysosomal protective protein | 0.1155 | 1 | 1 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.1041 | 0.8961 | 0.8961 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.1155 | 1 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0117 | 0.0552 | 0.0284 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0058 | 0.0014 | 0.0014 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0058 | 0.0014 | 0.0014 |
Entamoeba histolytica | protein kinase, putative | 0.0117 | 0.0552 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0117 | 0.0552 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0117 | 0.0552 | 0.0284 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.1155 | 1 | 1 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0058 | 0.0014 | 0.0014 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0117 | 0.0552 | 0.0284 |
Entamoeba histolytica | protein kinase, putative | 0.0087 | 0.0276 | 0.4871 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0117 | 0.0552 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.1155 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0117 | 0.0552 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0087 | 0.0276 | 0.4871 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0117 | 0.0552 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0117 | 0.0552 | 0.0538 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0117 | 0.0552 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.1155 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0117 | 0.0552 | 0.0552 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0117 | 0.0552 | 0.0552 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.