Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | histone deacetylase 3 | 0.0263 | 0.8954 | 0.6875 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0263 | 0.8954 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0263 | 0.8954 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0263 | 0.8954 | 0.8381 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0273 | 0.9399 | 0.8203 |
Brugia malayi | Histone deacetylase family protein | 0.0273 | 0.9399 | 1 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0214 | 0.6654 | 0.5 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0263 | 0.8954 | 0.8381 |
Trypanosoma brucei | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0273 | 0.9399 | 0.8203 |
Echinococcus granulosus | histone deacetylase 3 | 0.0263 | 0.8954 | 0.6875 |
Echinococcus granulosus | histone deacetylase 6 | 0.0273 | 0.9399 | 0.8203 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0263 | 0.8954 | 0.5 |
Echinococcus granulosus | histone deacetylase 1 | 0.0263 | 0.8954 | 0.6875 |
Echinococcus granulosus | histone deacetylase 6 | 0.0273 | 0.9399 | 0.8203 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0273 | 0.9399 | 0.8203 |
Schistosoma mansoni | histone deacetylase | 0.0263 | 0.8954 | 0.6875 |
Echinococcus multilocularis | histone deacetylase | 0.0273 | 0.9399 | 0.8203 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0263 | 0.8954 | 0.9527 |
Entamoeba histolytica | histone deacetylase, putative | 0.0263 | 0.8954 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.8954 | 0.9527 |
Giardia lamblia | Histone deacetylase | 0.0263 | 0.8954 | 0.5 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0273 | 0.9399 | 0.8203 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0286 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0263 | 0.8954 | 0.6875 |
Schistosoma mansoni | histone deacetylase | 0.0263 | 0.8954 | 0.6875 |
Plasmodium falciparum | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Loa Loa (eye worm) | histone deacetylase | 0.0273 | 0.9399 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.0273 | 0.9399 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0263 | 0.8954 | 0.5 |
Plasmodium falciparum | histone deacetylase 2 | 0.0273 | 0.9399 | 1 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0263 | 0.8954 | 0.9527 |
Leishmania major | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0263 | 0.8954 | 0.8381 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0263 | 0.8954 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0214 | 0.6654 | 0.708 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0273 | 0.9399 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0263 | 0.8954 | 0.8381 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0263 | 0.8954 | 0.5 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0263 | 0.8954 | 0.8381 |
Brugia malayi | Histone deacetylase 1 | 0.0263 | 0.8954 | 0.8381 |
Echinococcus granulosus | histone deacetylase | 0.0273 | 0.9399 | 0.8203 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0263 | 0.8954 | 0.5 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0263 | 0.8954 | 0.8381 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0273 | 0.9399 | 1 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0263 | 0.8954 | 0.8381 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0263 | 0.8954 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.6654 | 0.708 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0263 | 0.8954 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.0263 | 0.8954 | 0.8381 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0273 | 0.9399 | 0.8203 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0286 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.0273 | 0.9399 | 0.8203 |
Trypanosoma brucei | histone deacetylase 4 | 0.0273 | 0.9399 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0273 | 0.9399 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0273 | 0.9399 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0273 | 0.9399 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.