Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.3244 | 0 | 0.5 |
Echinococcus multilocularis | hedgehog | 0.4454 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 16 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis CIP 103471 | ChEMBL. | 9873650 |
MIC (functional) | > 16 ug ml-1 | Antimycobacterial activity against Mycobacterium avium CIP 103317 | ChEMBL. | 9873650 |
MIC (functional) | > 16 ug ml-1 | Antibacterial activity against Mycobacterium smegmatis CIP 103599. | ChEMBL. | 9873650 |
MIC (functional) | > 16 ug ml-1 | Antimycobacterial activity against Mycobacterium gordonae CIP 6427 | ChEMBL. | 9873650 |
MIC (functional) | > 16 ug ml-1 | Antimycobacterial activity against Mycobacterium marinum CIP 6423 | ChEMBL. | 9873650 |
MIC (functional) | > 16 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis CIP 103471 | ChEMBL. | 9873650 |
MTD50 (functional) | 0 ug ml-1 | Compound was tested for cytotoxicity against VERO cells; Not determined | ChEMBL. | 9873650 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.