Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | microsomal glutathione s-transferase | 0.6781 | 1 | 1 |
Trichomonas vaginalis | UDP-glucose 4-epimerase, putative | 0.0095 | 0 | 0.5 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0385 | 0.0435 | 0.0435 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.6781 | 1 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0385 | 0.0435 | 1 |
Trypanosoma brucei | UDP-galactose 4-epimerase | 0.0099 | 0.0006 | 0.5 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.038 | 0.0427 | 0.9831 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.038 | 0.0427 | 0.0427 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0385 | 0.0435 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.038 | 0.0427 | 0.0427 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.038 | 0.0427 | 0.0427 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.038 | 0.0427 | 0.9831 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.038 | 0.0427 | 0.0427 |
Entamoeba histolytica | UDP-glucose 4-epimerase, putative | 0.0095 | 0 | 0.5 |
Giardia lamblia | UDP-glucose 4-epimerase | 0.0099 | 0.0006 | 0.5 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0385 | 0.0435 | 0.0435 |
Leishmania major | udp-glc 4-epimerase, putative | 0.0099 | 0.0006 | 0.5 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0385 | 0.0435 | 0.0435 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0095 | 0 | 0.5 |
Trypanosoma cruzi | UDP-galactose 4-epimerase | 0.0095 | 0 | 0.5 |
Toxoplasma gondii | MAPEG family protein | 0.6781 | 1 | 1 |
Trypanosoma cruzi | UDP-galactose 4-epimerase, putative | 0.0095 | 0 | 0.5 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0095 | 0 | 0.5 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.038 | 0.0427 | 0.0427 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.6781 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.